呼吸系统 第二版 作者:(英)戴维斯,(英)穆瑞斯 主编 出版时间: 2011年版 丛编项: "以器官系统为中心"原版英文教材 内容简介 “以器官系统为中心”的医学教学模式是国际医学教育的趋势。本系列书是世界著名医药卫生出版集团爱思唯尔公司出版的一套“以器官系统为中心”的医学基础课程教材,共分为骨骼肌肉系统、心血管系统、呼吸系统、消化系统、泌尿系统、神经系统、内分泌系统七个分册。该套教材第1版出版后受到世界各地许多医学院校的欢迎,并被多家进行“以器官系统为中心”教学的医学院校选定为教材。第2版根据第1版出版后教师和学生的反馈意见,结合医学知识的更新进行了全新修订。在编写内容上,该系列教材强调基础与临床的整合。每一章节都是围绕着一个临床病例展开,通过对病人问题的呈现以及解决过程引出对相关知识的探究,从而使与器官系统结构、功能以及疾病相关的重要的基础医学知识得到了完善的整合。在版式安排上,图框中的病例资料与正文中的医学知识完美匹配,一步一步地激起读者的求知欲望。 目录 1 INTRODUCTION Introduction What is respiration? The need for respiration Diffusion in respiration and the circulation Timing in the circulation and respiration Basic science of respiration Drugs 2 STRUCTURE OF THE RESPIRATORY SYSTEM,RELATED TOFUNCTION Introduction The upper airways The intrathoracic airways Blood vessels Pulmonary hypertension The lymphatics The nerves Gross structure of the respiratory system Pleurisy The diaphragm and chest wall How breathing is brought about Embryology Air-conditioning Metabolic activity Metabolism of circulating biologically activesubstances Non-respiratory functions 3 ELASTIC PROPERTIES OF THE RESPIRATORY SYSTEM Introduction Intrapleural pressure (Ppl) Static lung compliance (CL) The effect of disease The physical basis of lung compliance 4 AIRFLOW IN THE RESPIRATORY SYSTEM Introduction How airflow is brought about The nature of airflow The major determinant of flow - radius Airways resistance and obstructive pulmonary disease The clinical situation Sites of airways resistance Asthma and airways smooth muscle Bronchomotor tone Pharmacological treatment of asthma Clinical definitions Bronchitis and mucus Emphysema and radial traction Intrapleural pressure and cough Clinical tests for changes in resistance Work of breathing 5 VENTILATION OF THE RESPIRATORY SYSTEM: THE IMPORTANCE OFITS LACK OF UNIFORMITY IN DISEASE Introduction Spirometric abnormalities in disease Uneven distribution Dead space. Alveolar dead space in disease The Bohr equation Factors affecting physiological dead space Alveolar ventilation and respiratory exchange The alveolar gas equation Distribution of inspired gas Other factors influencing distribution 6 GAS EXCHANGE BETWEEN AIR AND BLOOD:DIFFUSION The path from air to tissue Lung disease and diffusion Fick's Law of Diffusion Measuring transfer factor Treating diffusion difficulties Carbon dioxide and other gases 7 THE PULMONARY CIRCULATION: BRINGING BLOOD AND GASTOGETHER The functions of the pulmonary circulation The anatomy of the pulmonary circulation Matching ventilation and perfusion Distribution of blood flow through the lungs Regional differences in ventilation in the lungs Ventilation/perfusion matching and its effect on blood O and CO content Shunt 8 CARRIAGE OF GASES BY THE BLOOD AND ACID/BASE BALANCE Introduction Oxygen transport Dissolved oxygen: do we really need Hb and why keep it in red cells? Carbon dioxide transport Acid-base balance 9 CHEMICAL CONTROL OF BREATHING Introduction Oxygen lack Carbon dioxide excess 10 NERVOUS CONTROL OF BREATHING Introduction The rhythm generator Pattern of breathing in COPD The respiratory 'centres' The medullary groups Conscious control of breathing Respiratory muscle innervation Neuromuscular disorders Vagal reflexes Dyspnoea Other reflexes 11 LUNG FUNCTION TESTS: MEASURING DISABILITY Introduction Spirometry Flow measurements Plethysmography Lung mechanics Transfer factor (diffusing capacity) Blood gases Gas washouts Exercise testing Challenge tests Appendix: some basic science Glossary Index
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